X-linked hypohidrotic ectodermal dysplasia is an inherited disorder that affects tissues derived from the ectoderm and causes abnormal development of the skin, hair, nails, teeth, and exocrine glands.
Trapped neutrophil syndrome is an inherited neutropenia in Border Collies that compromises the immune system, leading to chronic infection in affected dogs.
Adverse owner-reported behaviors (such as seizure, “glazing over”, episodic biting, and general loss of clarity) in the Belgian Malinois have been associated with certain genetic polymorphisms in the dopamine transporter gene.
Pyruvate kinase deficiency (PKDef) is an inherited hemolytic anemia caused by a defect in the enzyme pyruvate kinase. Signs in affected dogs may include lack of energy and fatigue in dogs that appear otherwise fit.