Progressive retinal atrophy (PRA) is characterized by degeneration of the retina resulting in progressive vision loss leading to total blindness. A deletion in the CACNA1F gene is one cause of PRA in racing Greyhounds. There are many known genetic causes for PRA in dogs.
Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.
Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.
White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.