Collie Eye Anomaly (CEA), also known as choroidal hypoplasia, is a heritable disorder that can result in abnormal development of inner structures of the eye. This genetic variant is associated with CEA in multiple breeds.
Cerebellar Degeneration-Myositis Complex (CDMC) is a heritable disorder that causes neurological signs that manifest as early as 10 weeks of age in affected Nova Scotia Duck Tolling Retrievers.
Cardiac Laminopathy (CLAM) is a fatal heritable condition that results in dilated cardiomyopathy and sudden death in young adult Nova Scotia Duck Tolling Retrievers
Chondrodystrophy, a trait that is characterized by a short-legged phenotype, also impacts the health of dogs. Dogs with at least one copy of the mutation have premature disc degeneration and increased susceptibility to disc herniation.
Progressive rod-cone degeneration (PRCD) is an inherited form of late-onset progressive retinal atrophy (PRA) that has been identified in many dog breeds.
Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.