Rottweiler

Intensity Dilution

The intensity coat color gene variant causes an extreme dilution of phaeomelanin (red or yellow pigment), resulting in a cream to white coat in dogs.

Parentage/Genetic Marker Report

This DNA-based parentage test uses microsatellite marker analysis to compare the DNA profile of an offspring to the profiles of possible parents.

Furnishings and Improper Coat

A dominant variant of the R-spondin-2 gene produces the longer mustache and eyebrows seen in wire-haired dogs and other breeds.

Curl (C1, C2)

Two variants in the Keratin-71 gene are associated with curly hair in dogs. Dogs with these curl variants have curly coats or wavy coats depending on how many copies of the allele they possess.

Coat Length

Five recessive variants in the fibroblast growth factor-5 (FGF5) gene are associated with long hair phenotypes in dogs.

Piebald/White Spotting (S Locus)

White spotting patterns that occur in many dog breeds do not have a uniform genetic basis, and the genetics are complex. In piebald/parti/random white spotting, the extent of white pattern expression varies, and markings are often asymmetrical.

Merle

Merle is an incompletely dominant coat color pattern characterized by irregularly shaped patches of diluted pigment and solid color.

Dominant Black (K Locus)

The Dominant Black gene (K Locus) affects pigment switching between eumelanin (black) and phaeomelanin (red or yellow) by interacting with the Agouti and MC1R genes.