X-linked hypohidrotic ectodermal dysplasia is an inherited disorder that affects tissues derived from the ectoderm and causes abnormal development of the skin, hair, nails, teeth, and exocrine glands.
Trapped neutrophil syndrome is an inherited neutropenia in Border Collies that compromises the immune system, leading to chronic infection in affected dogs.
Pyruvate kinase deficiency (PKDef) is an inherited hemolytic anemia caused by a defect in the enzyme pyruvate kinase. Signs in affected dogs may include lack of energy and fatigue in dogs that appear otherwise fit.
This inherited primary open angle glaucoma in Beagles results from a mutation in the gene ADAMTS10. The condition is characterized by increased pressure in the eye; nerve damage, vision loss, lens subluxation, and blindness may result.