Quick Summary
Click here for Price and Turnaround Time
Phenotype: Affected dogs may appear mostly healthy but may be prone to increased bleeding tendency.
Mode of Inheritance: Autosomal recessive
Alleles: N = Normal, FVII = Factor VII deficiency
Breeds appropriate for testing: Beagle, Airedale, Alaskan Klee Kai, American Foxhound, Finnish Hound, German Wirehaired Pointer, Giant Schnauzer, Irish Water Spaniel, Japanese Spitz, Miniature Schnauzer, Papillon/Phalene, Sealyham Terrier, Scottish Deerhound, Welsh Springer Spaniel
Explanation of Results:
- Dogs with N/N genotype will not have factor VII deficiency and cannot transmit this FVII variant to their offspring.
- Dogs with N/FVII genotype will not have factor VII deficiency, but are carriers. They will transmit this FVII variant to 50% of their offspring. Matings between two carriers are predicted to produce 25% factor VII deficiency-affected puppies.
- Dogs with FVII/FVII genotype will have factor VII deficiency, a mild to moderate blood clotting disorder, and will transmit this FVII variant to all of their offspring.
Results of this test can be submitted to the OFA (Orthopedic Foundation for Animals)
Beagle Health Panel
$130 per animal
Factor VII is a clotting factor synthesized in the liver that is necessary to initiate blood coagulation when vascular injury occurs. Factor VII deficiency is a mild to moderate inherited blood clotting disorder present in Beagles and several other dog breeds (see "Breeds appropriate for testing" list above). It is inherited as an autosomal recessive, thus both females and males can be affected if they carry 2 copies of the defective gene; individuals with only 1 copy of the mutation are not affected.
