Overview
The Veterinary Genetics Laboratory (VGL), in collaboration with Dr. Niels C. Pedersen and staff, has developed a panel of short tandem repeat (STR) markers that will determine genetic diversity across most of the genome and in the Dog Leukocyte Antigen (DLA) class I and II regions. This test panel will be useful to breeders who wish to track heterozygosity and genetic diversity of their breed as a long-term goal
Genetic diversity testing of Magyar Agár is now in the data collection phase. During this phase, we will continue to test more registered dogs to build genetic data necessary to provide breeders with an accurate assessment of genetic diversity in their breed. We are accepting dogs from all regions of the world. At the time this report was written we had tested 59 Magyar Agár, which should provide a preliminary picture of the genetic makeup of the breed. Thirty-nine dogs were from Finland, 14 from Hungary, and the origins of six dogs were not provided. The data derived from these 59 dogs is likely to change as more dogs are tested, but only a little and by additions of lower incidence alleles and haplotypes. The report will be updated until no further changes occur.
Price
$50 one test per animal
This is the cost for the dogs that will be tested in the research phase. Once the research phase is complete, the test will be offered at the regular rate of $80.
Results reported as:
Short tandem repeat (STR) loci: A total of 33 STR loci from across the genome were used to gauge genetic heterogeneity and existing genetic diversity within an individual and across the breed. The alleles inherited from each parent are displayed graphically to highlight heterozygosity and genetic diversity in individuals and breed-wide.
DLA haplotypes: Seven STR loci linked to the DLA class I and II genes were used to identify genetic differences in a region that regulates immune responses and self/non-self-recognition. Problems with self/non-self-recognition, along with non-genetic factors in the environment, are responsible for autoimmune disease, allergies, and susceptibility to infectious agents.
Internal Relatedness: The IR value is a measure of the genetic relatedness of an individual's parents. The value takes into consideration both heterozygosity of alleles at each STR loci and their relative frequency in the population. Therefore, IR values heterozygosity over homozygosity and uncommon alleles over common alleles. IR values are unique to each dog and two individuals from different sources may have identical IR values but a very different genetic makeup.
Report
Report issued April 17, 2019. Daily updated statistics are here.
